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KMID : 0359720220400040331
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Journal of the Korean Neurological Association
2022 Volume.40 No. 4 p.331 ~ p.333
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MOG Antibody-Positive Myelopathy as a Paraneoplastic Manifestation of Lymphoma
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Gil So-Dam
Seok Jung-Im
Kim Yo-Sep
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Abstract
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Although myelin oligodendrocyte glycoprotein antibodyassociated disease (MOGAD) is an autoimmune demyelinating disease, it may occur as a paraneoplastic syndrome in rare instances. A 80yearold woman presented with paresthesia and weakness of four extremities for 10 days. Spine magnetic resonance imaging showed longitudinally extensive transverse myelitis. Laboratory tests revealed positive MOG antibodies. Both highdose intravenous methylprednisolone and plasma exchange were not effective and further evaluation showed lymphoma. Herein, we reported a case of MOGpositive paraneoplastic myelopathy with lymphoma.
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KEYWORD
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Paraneoplastic syndromes, Myelin oligodendrocyte glycoprotein, Myelitis
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